We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
8
Omega-3 reduces heart attack risk
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
8
Omega-3 fatty acids and heart disease
Associations of circulating fatty acids with incident coronary heart disease: a prospective study of 89,242 individuals in UK Biobank.
We delved into how different types of fatty acids influence the risk of coronary heart disease (CHD) using data from a large study of over 89,000 adults.
Our findings revealed that omega-3 fatty acids seemed to lower the risk of CHD, standing out among other fatty acids. Interestingly, saturated and monounsaturated fats did show a positive link to CHD, but this was largely connected to their effect on triglyceride levels.
Overall, omega-3 fatty acids might offer a protective benefit against heart disease.
Read More
Most Useful Reviews
9
Enhances heart function
3 people found this helpful
The quality is excellent; the ingredients are natural and economical. The large packaging offers effective benefits for the body and energy. The taste is excellent, and it's beneficial for those over 15 years old, especially for heart health.
Read More
7.5
Reliable omega supplement
2 people found this helpful
I am thoroughly satisfied with Now Foods' Omega-3. These capsules are rich in polyunsaturated fatty acids essential for heart health. You only need one capsule daily, which is convenient, and there's no unpleasant taste or odour. The quality from the Now brand is consistently good, and this product is no exception. Highly recommend trying it for high-quality omega-3.
Read More
9
Improved heart health
1 people found this helpful
Omega 3 from fish oil has remarkable benefits for the heart, arteries, and muscles. It significantly aids the elderly by alleviating fatigue and exhaustion, enhancing memory, strengthening nerves, and assisting with arthritis. The packaging is satisfactory and the ingredients are good. Prioritise your health by maintaining a healthy, balanced diet and ensuring regular exercise.
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
9
Omega-3 benefits for smokers' heart health
Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking.
We explored whether icosapent ethyl (IPE), a refined omega-3 fatty acid, could lower heart attack risk among cigarette smokers. In the REDUCE-IT trial, over 8,000 statin-treated patients were randomly assigned to receive either IPE or a placebo for nearly five years.
Our findings showed that IPE significantly reduced cardiovascular events by 25%, especially for current and former smokers. Participants using IPE experienced heart attack rates similar to non-smokers, suggesting that IPE may help lessen cardiovascular risks associated with smoking.
Read More
8
Omega-3 reduces heart attack risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
We investigated whether icosapent ethyl is beneficial in reducing heart attack rates among patients with well-managed low-density lipoprotein cholesterol (LDL-C).
Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.
Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
Read More
8
Omega-3 reduces heart attack risk
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
8
Omega-3 improves heart attack outcomes
Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT.
We observed that icosapent ethyl, a type of omega-3 fish oil, plays a significant role in reducing heart attack risk among patients with atherosclerotic cardiovascular disease (ASCVD). In a study involving almost 5,800 participants, those taking icosapent ethyl experienced lower rates of major adverse cardiovascular events (MACE) compared to those on placebo.
The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
The quality is excellent; the ingredients are natural and economical. The large packaging offers effective benefits for the body and energy. The taste is excellent, and it's beneficial for those over 15 years old, especially for heart health.
Read More
7.5
Reliable omega supplement
2 people found this helpful
I am thoroughly satisfied with Now Foods' Omega-3. These capsules are rich in polyunsaturated fatty acids essential for heart health. You only need one capsule daily, which is convenient, and there's no unpleasant taste or odour. The quality from the Now brand is consistently good, and this product is no exception. Highly recommend trying it for high-quality omega-3.
Read More
9
Improved heart health
1 people found this helpful
Omega 3 from fish oil has remarkable benefits for the heart, arteries, and muscles. It significantly aids the elderly by alleviating fatigue and exhaustion, enhancing memory, strengthening nerves, and assisting with arthritis. The packaging is satisfactory and the ingredients are good. Prioritise your health by maintaining a healthy, balanced diet and ensuring regular exercise.
Read More
9
Boosts heart rate
1 people found this helpful
I can honestly say that this product is remarkable. Within a month of using it, my energy levels skyrocketed, hair loss diminished, and concentration improved. The taste is natural for fish oil, and the 90-day supply is significantly beneficial for my heart.
Read More
7.5
Improves heart performance
1 people found this helpful
The quality of Omega is exceptional for any age, and it’s incredibly beneficial. I've noticed improvements in my hair, nails, and skin health. My heart appears to function better and skin inflammation has disappeared. I am genuinely satisfied with the quality.
A heart attack, also known as myocardial infarction, occurs when blood flow to a part of the heart is blocked, often by a blood clot. This interruption can damage or destroy part of the heart muscle, leading to serious health complications or death if not treated promptly. Common symptoms include chest pain, shortness of breath, nausea, and lightheadedness. Risk factors include high blood pressure, high cholesterol, smoking, diabetes, and a sedentary lifestyle.
Preventing a heart attack largely revolves around maintaining a heart-healthy lifestyle. Regular exercise, a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with managing stress, can significantly lower the risk. Furthermore, understanding your personal risk factors and engaging with healthcare professionals for regular check-ups can be crucial in both prevention and early detection. If you suspect someone is having a heart attack, it's important to call emergency services immediately, as timely treatment is vital for survival and recovery.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Omega-3 fish oil has been widely studied for its potential benefits in heart health, particularly in reducing the risk of heart disease and heart attacks. Research suggests that the omega-3 fatty acids found in fish oil can help decrease triglyceride levels, lower blood pressure, and reduce arterial plaque buildup—all factors that can contribute to heart problems. Several clinical trials and meta-analyses indicate that regular supplementation with omega-3 fatty acids may lead to a lower risk of heart attack, especially for individuals with existing heart conditions or high-risk factors for heart disease.
However, it's essential to note that while omega-3 fish oil can be beneficial, it should not be viewed as a standalone treatment for heart issues. Those at risk for heart attacks should consider omega-3 supplementation as part of a comprehensive heart health strategy that includes a balanced diet, regular exercise, and appropriate medical care. If you're considering adding omega-3 fish oil to your regimen, consult with a healthcare professional to ensure it's suitable for your individual health needs.
Based on user reviews, individuals taking Omega-3 supplements for heart health report varying timelines for noticeable results. Many users indicate that significant benefits can be experienced as soon as one month after starting the supplement. For instance, one reviewer shared that they observed improvements in energy levels and heart function within a month of usage Read Review. Others have noted benefits such as reduced fatigue and improved cholesterol levels after consistent use over several months to a year Read Review.
It's important to remember that results can depend on individual health conditions, dietary habits, and lifestyle factors. Some users emphasize the importance of long-term commitment to supplementation for sustained benefits to heart health, with many suggesting continuous use for minimum periods of several months or more Read Review. Regular intake coupled with a healthy diet and exercise can further enhance the effectiveness of Omega-3 for heart health.
The use of omega-3 fatty acids, particularly in the forms of icosapent ethyl and eicosapentaenoic acid (EPA), is increasingly supported by scientific research as a viable supplement for reducing heart attack risk. A significant study from the REDUCE-IT trial demonstrated that icosapent ethyl effectively lowered cardiovascular complications among statin-treated patients, regardless of their cholesterol levels, suggesting notable heart attack prevention capabilities [1]. Additionally, evidence indicates that EPA supplementation can improve heart function after heart attacks, although more research is necessary to confirm long-term benefits in humans [11].
Moreover, various studies have reported the positive effects of omega-3 fatty acids on specific populations, such as African Americans, showing substantial reductions in heart attack risk [2]. While the overall benefits of omega-3 supplementation remain debated—especially concerning how remarkably they lower certain cardiovascular outcomes—the siding towards their effectiveness in heart attack prevention is noteworthy [12]. This combination of findings provides a robust case for considering these supplements as part of a heart-healthy regimen.
Based on user reviews, many individuals have reported a variety of improvements in their symptoms after using Omega-3 supplements. Users frequently highlight enhanced heart health, with specific mentions of reduced cholesterol levels and alleviation of inflammation, critical aspects for maintaining cardiovascular wellbeing Read Review, . Additionally, others have experienced boosts in overall energy, with one user noting a significant increase in vitality, changes in concentration, and even improvements in skin and hair health Read Review, .
It's important to acknowledge that individual results can vary. While some users have witnessed improvements in a matter of weeks, such as reduced fatigue and increased mental clarity Read Review, others report ongoing benefits after prolonged use spanning several months . Overall, personal experiences suggest that incorporating Omega-3 supplements can lead to significant health benefits, although results may differ based on factors such as adherence to a healthy diet and individual health conditions.
Based on user reviews, many individuals combining Omega-3 supplements with other nutrients have reported significant benefits for heart health. For instance, several users specifically mentioned taking Omega-3 alongside Vitamin D, highlighting that this combination effectively lowers cholesterol and positively impacts heart health and inflammation Read Review. This synergy seems to enhance overall wellness, making it a go-to choice for those aiming to optimize cardiovascular function while also addressing conditions like fatigue and skin health Read Review.
Other reviewers noted improvements in their overall health after integrating Omega-3 with their regular supplements. They appreciated the combination's effectiveness at managing cholesterol levels and inflammation, affirming the belief that Omega-3 supports heart health when used consistently with a balanced diet Read Review. Users expressed satisfaction in the absence of any unpleasant fishy taste, making it a suitable addition to their daily health regimen inspired by positive recommendations from healthcare professionals Read Review. Overall, user experiences suggest that blending Omega-3 supplements with other vitamins can enhance the heart's wellbeing and manage health better.
The optimal dose of Omega-3 fish oil for treating heart attack specifically isn't universally established, but research indicates promising results with certain formulations like icosapent ethyl. For instance, the REDUCE-IT trial found that patients taking icosapent ethyl experienced a significant reduction in heart attack rates and major cardiovascular events, highlighting its effectiveness for those managing atherosclerotic cardiovascular disease ([4]). The recommended dose in this context has typically been around 4 grams daily, which appears beneficial in lowering the risk of heart issues, particularly when combined with statin therapy ([6]).
Moreover, a study examining the effects of omega-3s in African Americans noted that supplementation significantly reduced heart attack risk, suggesting that individual responses may vary based on demographic factors ([2]). While high doses of omega-3 supplements may help those at higher risk or with certain conditions, it's essential to consult with a healthcare provider to determine the best personal regimen. Overall, promising findings point to omega-3 fish oil, especially in purified forms like EPA, as a potential adjunctive treatment in managing heart health, particularly in high-risk populations ([12]).
9
Boosts heart rate
1 people found this helpful
I can honestly say that this product is remarkable. Within a month of using it, my energy levels skyrocketed, hair loss diminished, and concentration improved. The taste is natural for fish oil, and the 90-day supply is significantly beneficial for my heart.
7.5
Less fatigue noted
1 people found this helpful
Excellent value for money and a fantastic supplement! It aids heart health while improving skin and hair conditions. After nearly a year of use, I've noticed a significant improvement in my overall health and reduced fatigue despite training several times a week.
7.5
Improves overall well-being
6 people found this helpful
This is the third time I have purchased this after my doctor's recommendation. I noticed significant improvement in my condition, and my skin is healthier. The high-quality ingredients, including Omega-3 fish oil and vitamin D, are beneficial for cholesterol management, inflammation, heart health, and more. It's a valued addition to my routine.
7.5
Reduces cholesterol effectively
6 people found this helpful
Omega 3 is widely recognised as beneficial, so I decided to boost my health with a course of it, although doctors advise regular intake. The benefits are significant—cholesterol reduction and a positive impact on the heart, alongside general inflammation relief. One capsule daily is sufficient. The large plastic jar has a convenient lid. The capsules are sizeable and firm; I find them tough to swallow, so next time I might choose liquid or smaller capsules.
9
Improved heart health
1 people found this helpful
Omega 3 from fish oil has remarkable benefits for the heart, arteries, and muscles. It significantly aids the elderly by alleviating fatigue and exhaustion, enhancing memory, strengthening nerves, and assisting with arthritis. The packaging is satisfactory and the ingredients are good. Prioritise your health by maintaining a healthy, balanced diet and ensuring regular exercise.
7.5
Overall health benefit
1 people found this helpful
This Omega-3 along with Vitamin D is remarkable, and I have purchased it multiple times. It is noted for lowering cholesterol and positively influencing heart health and inflammation. The quality is superb, and the packaging is standard, lasting a long time without a fishy taste. It maintains health for any age, and I even give it to children.
7.5
Good taste
These supplements have good quality ingredients with no fish smell. They significantly benefit my cholesterol levels, reduce inflammation, and support my heart health, all while tasting great.
7.5
Convenient packaging
I highly recommend this product! The quality is good, and the delivery is fast. At my age, I’m concerned about health, seeking supplements that enhance immunity. The dosage is one tablet a day and is well-packaged to prevent oxidation, making it easy to store. It appears to be more effective for heart health and inflammation than other multivitamins, with no discernible taste because it’s pill-based.
8
Omega-3 reduces heart attack risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
We investigated whether icosapent ethyl is beneficial in reducing heart attack rates among patients with well-managed low-density lipoprotein cholesterol (LDL-C).
Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.
Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
8
EPA shows promise for heart health
Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats.
We looked into how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, could support heart health after a heart attack. In a study with male rats, we induced heart attacks and then gave some of them EPA for 12 weeks.
The results showed that EPA helped improve heart function and maintained key components in mitochondria, which are vital for energy production in heart cells. While EPA treatment showed promise in preserving heart structure and energy levels, the long-term benefits in humans still need further exploration.
8
Omega-3 reduces heart attack risk
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
9
Omega-3s' mixed effects on heart health
Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health.
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
8
Omega-3 improves heart attack outcomes
Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT.
We observed that icosapent ethyl, a type of omega-3 fish oil, plays a significant role in reducing heart attack risk among patients with atherosclerotic cardiovascular disease (ASCVD). In a study involving almost 5,800 participants, those taking icosapent ethyl experienced lower rates of major adverse cardiovascular events (MACE) compared to those on placebo.
The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
7
Omega-3 and statin heart benefits
Assessing the Efficacy of Omega-3 Fatty Acids + Statins vs. Statins Only on Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of 40,991 Patients.
We examined the effects of adding omega-3 fatty acids to statin therapy for heart health by reviewing 14 randomized controlled trials with about 40,991 patients. Our analysis showed that this combination significantly reduced events like heart attacks, unstable angina, and cholesterol levels compared to statins alone.
However, we found no major differences in deadly strokes or coronary surgeries. This suggests that while omega-3 supplementation may offer some benefits, it doesn't dramatically impact all cardiovascular outcomes.
References
Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
Sun S, Hara A, Johnstone L, Hallmark B, Watkins JC, et al. Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation. Nutrients. 2024;16. 10.3390/nu16172933
Ahmadi M, Askari VR, Shahri B, Mousavi Noghab SM, Jarahi L, et al. Omega-3 fatty acids effectively mitigate high-sensitivity C-reactive protein (hs-CRP) biomarker of inflammation in acute myocardial infarction patients: a randomized, double-blind, placebo-controlled clinical trial. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:881. 10.1007/s00210-024-03330-1
Burger PM, Bhatt DL, Dorresteijn JAN, Koudstaal S, Mosterd A, et al. Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT. Eur Heart J Cardiovasc Pharmacother. 2024;10:488. 10.1093/ehjcvp/pvae030
Bernhard B, Heydari B, Abdullah S, Francis SA, Lumish H, et al. Effect of six month's treatment with omega-3 acid ethyl esters on long-term outcomes after acute myocardial infarction: The OMEGA-REMODEL randomized clinical trial. Int J Cardiol. 2024;399:131698. 10.1016/j.ijcard.2023.131698
Irfan A, Haider SH, Nasir A, Larik MO, Naz T. Assessing the Efficacy of Omega-3 Fatty Acids + Statins vs. Statins Only on Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of 40,991 Patients. Curr Probl Cardiol. 2024;49:102245. 10.1016/j.cpcardiol.2023.102245
Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. 10.3390/nu15194235
Jin D, Trichia E, Islam N, Lewington S, Lacey B. Associations of circulating fatty acids with incident coronary heart disease: a prospective study of 89,242 individuals in UK Biobank. BMC Cardiovasc Disord. 2023;23:365. 10.1186/s12872-023-03394-6
Lyytinen AT, Yesmean M, Manninen S, Lankinen M, Bhalke M, et al. Fatty fish consumption reduces lipophilic index in erythrocyte membranes and serum phospholipids. Nutr Metab Cardiovasc Dis. 2023;33:1453. 10.1016/j.numecd.2023.04.011
Chiusolo S, Bork CS, Gentile F, Lundbye-Christensen S, Harris WS, et al. Adipose tissue n-3/n-6 fatty acids ratios versus n-3 fatty acids fractions as predictors of myocardial infarction. Am Heart J. 2023;262:38. 10.1016/j.ahj.2023.03.019
Kobara M, Shiraishi T, Noda K, Toba H, Nakata T. Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats. J Cardiovasc Transl Res. 2023;16:816. 10.1007/s12265-023-10363-z
Rodriguez D, Lavie CJ, Elagizi A, Milani RV. Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health. Nutrients. 2022;14. 10.3390/nu14235146
Bassuk SS, Manson JE. Marine omega-3 fatty acid supplementation and prevention of cardiovascular disease: update on the randomized trial evidence. Cardiovasc Res. 2023;119:1297. 10.1093/cvr/cvac172
Nishizaki Y, Miyauchi K, Iwata H, Inoue T, Hirayama A, et al. Study protocol and baseline characteristics of Randomized trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, the combination of a randomized control trial and an observational biomarker study. Am Heart J. 2023;257:1. 10.1016/j.ahj.2022.11.008
Miller M, Bhatt DL, Steg PG, Brinton EA, Jacobson TA, et al. Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking. Eur Heart J Cardiovasc Pharmacother. 2023;9:129. 10.1093/ehjcvp/pvac045
Yokoyama Y, Kuno T, Morita SX, Slipczuk L, Takagi H, et al. Eicosapentaenoic Acid for Cardiovascular Events Reduction- Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. J Cardiol. 2022;80:416. 10.1016/j.jjcc.2022.07.008